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Clinic |
Moscow, m. VDNH, territory of the All-Russia Exhibition Centre (495)745-10-77, 103-03-40 syphilis@yandex.ru
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 Analyses to syphilis |
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Analyses to syphilis
Analyses to syphilis consist of clinical and laboratory data:
a study for pale treponemu;
a study of the blood on RW (Wasserman reaction);
RIF (reaction of immune fluorescence);
RIPT (reaction of the immobilization of pale treponem).
Diagnostics of syphilis of primary period is carried out by investigating the discharge of solid chancre, puncture specimen of regional lymphatic it is main.
In diagnostics of syphilis of second period the material of papular, pustulous elements, erosive and hypertrophic papules of the skin and the mucous membranes is investigated.
Analyses to syphilis by the bacterioscopic method (microscopic) are carried out with the aid of the detection of pale treponemy in the dark-field microscope.
The treponemnym methods of diagnostics of syphilis include:
the reaction of Wasserman (RW);
the reaction of immunofluorescence (RIF).
RW (Wasserman reaction) has great significance for affirming the diagnosis of syphilis when the active manifestations of disease, development of concealed (latent) syphilis, effectiveness of the conducted treatment of syphilis are present. Is also RW important for the preventive maintenance of innate syphilis.
Wasserman reaction is positive in 100% of sick with syphilis second period, with early innate syphilis, in 70%-80% of patients with tertiary syphilis.
The treponemnym method of analyses to syphilis is also the reaction of immunofluorescence (RIF). RIF is the most highly sensitive method of diagnostics of syphilis and becomes positive already with primary seronegative syphillis.
RIF it is positive with second syphilis, innate syphilis in 100%, with tertiary syphillis - in 95%-100%, with the late forms of syphilis (internal organs, syphilis of nervous system) - in 97%-100%.
RIF adapts also for the analysis of concealed syphilis, late syphilis, the atypical, difficult for diagnostics cases.
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