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© At use of materials of a site the hyperlink is obligatory SyphilisSyphilis - a chronic infectious disease. At a syphilis the leather(skin), mucous, internal bodies, immunaya system, bones and nervous systems is amazed. The activator - pale Treponema.  Pale treponema (Treponema pallidium) belongs to order Spirochaetales, family Spirochaetaceae, kind Treponema. Morphologically pale treponema (pale spirochaeta) is differed from the saprofitiruyushchikh spirochaetae.
The most frequent way of infection by syphilis - sexual, with various forms of sexual contacts. Infection by syphilis occurs through the small genital or ekstragenital'nye defects of the skin or through the epithelium of mucous membrane with the contact with the solid chancre, the erosive papules on the skin and the mucous membranes of sex organs, cavity of mouth, by the wide condylomas, which contain a significant quantity of pale treponem. 
In the saliva pale treponemy can find only in the case, when there are precipitations on the mucous membrane of the cavity of mouth. The syphilis can be caught through sperm of the patient at absence at him(it) seen changes on genitals. Infection with a syphilis can seldom take place at close household contact, in unusual cases - through subjects of use. Infection with a syphilis through milk of the feeding woman sick of a syphilis is possible. Cases of infection by a syphilis through urine and sweat it is not marked. 
A syphilis from the moment of infection is the general(common) infectious disease which lasts at in the untreated patients many years and differs wavy current with change of the periods of an aggravation.
 During an aggravation of illness on mucous membranes, a leather(skin), in internal bodies active displays of a syphilis are observed.
One of principal causes of changes of clinic, duration of the incubatory period, the latent current of a syphilis, often application of antibiotics, change immunogo the status of an organism and other factors is. Classical current of a syphilis is characterized by alternation of active displays of disease with the latent period. The classical course of syphillis is characterized by the alternation of the active manifestations of disease with the latent period. Klassfikatsiya of the course of syphilis is divided into the incubative period, the primary, second and tertiary periods. See. Stages of a syphilis In the primary period appears the first clinical sign of syphilis - solid chancre (in that place, where pale treponema it penetrated in the organism). The disappearance of solid chancre speaks, that syphilis passed into the latent stage, during which in the organism occurs the stormy multiplication of pale treponem. The second period of syphilis comes usually 5-9 weeks after the appearance of a solid chancre (primary syphiloma) and continues without the treatment of 3-5 years. The course of second syphilis is undulating: the period of active manifestations is changed by the concealed form of syphillis. For the latent period characteristically the absence of clinical it is indicative syphilis and only positive serological reactions of the blood testify about the flow of infectious process. The clinical signs of tertiary syphillis can appear many years after the prolonged asymptomatic course of disease from the moment of infection by syphilis. By the main reason, which influences the formation of tertiary syphillis, is absence or defective treatment of patients the earlier forms of syphilis. |